In a latest examine revealed in Nature Digital Medicine, researchers highlighted a possible technique for utilizing a sensible bathroom platform, Coronavirus: Integrated Diagnostic (COV-ID), for passive monitoring of coronavirus illness 2019 (COVID-19).
The surge in extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections has warranted widespread, frequent, and continued testing to determine and mitigate the outbreaks of novel epidemics. Although nasal middle-turbinate and nasopharyngeal swabs are routinely obtained for traditional COVID-19 testing, they’re related to elevated affected person discomfort and require guide assortment.
The persistent nature of the pandemic might result in psychological fatigue, reducing public sensitivity towards COVID-19 management. In this regard, passive surveillance methods corresponding to absolutely automated sensible bathrooms that allow the detection of SARS-CoV-2 ribonucleic acid (RNA) in fecal matter might be a precious instrument in COVID-19 diagnostics.
Notably, earlier research have reported that SARS-CoV-2 may be detected in feces even after the decision of pulmonary signs, and roughly 5 weeks after the SARS-CoV-2 RNA detection exams yield destructive outcomes.
Of curiosity, a earlier publication of the authors of the current examine confirmed that sensible house occupants are extra accepting of sensible bathrooms. Thus, the staff envisioned passive sensible toilet-based testing as a key technique in advancing precision health-based COVID-19 diagnostics.
Study: Smart bathrooms for monitoring COVID-19 surges: passive diagnostics and public well being. Image Credit: Pixel-Shot / Shutterstock
About the examine
In the current examine, researchers reported the potential use of sensible bathrooms for passive and automatic COVID-19 analysis and longitudinal surveillance.
The COVI-ID sensible bathroom platform contains bidet-style mountable attachments for simple set up in extremely populated public areas corresponding to procuring complexes, sports activities arenas, hospitals, and colleges. They don’t want the substitute of the prevailing infrastructure. The sensible bathrooms have modules for absolutely automized and fecal specimen assortment and ultrafast SARS-CoV-2 RNA detection utilizing in situ nucleic acid amplification exams (NAAT). In addition, sensible bathroom know-how ensures environment friendly sanitization.
Smart bathrooms have in-built Quick Response (QR) codes which may be scanned when a person sits all the way down to defecate, and stool samples may be mechanically obtained. Within minutes, the check findings are obtained and uploaded to a centralized and anonymized tracing community. These tracing networks might be augmented to yield real-time knowledge for figuring out COVID-19 prevalence. This would help in stopping epidemic and native outbreaks by detecting the etiological brokers.
The COV-ID bathroom will function a centralized diagnostic heart in important companies to detect COVID-19 an infection amongst the asymptomatic populations and to facilitate early analysis and isolation. Stool sampling will probably be automated with a fast turn-around time for viral RNA testing, and the bathroom seat/surfaces will probably be sanitized in between customers. The person will register with the well being portal or a tracing community (which may be carried out on a cellular gadget whereas on the bathroom), which is able to then alert them to their check outcomes (ideally inside 15 min), hyperlink them with medical care, present recommendation and pointers from physicians for isolation. Aggregate knowledge can be used for inhabitants surveillance to evaluate neighborhood burden.
Furthermore, the tracing system of the COV-ID platform might be linked by way of Bluetooth to Google and Apple units and uploaded to particular person smartphones, if people consented to supply their cellular numbers. Individuals with optimistic check outcomes would even be offered data on the required quarantine protocols and confirmatory exams.
Certain stipulations should be met for the usage of sensible bathrooms for COVID-19 surveillance. First, the turnaround time have to be minimal (ideally quarter-hour). This is accomplished through the use of ultrafast velocity NAAT for viral RNA detection, which shortens detection time from a number of hours in commonplace NAAT strategies corresponding to polymerase chain response (PCR) to lower than quarter-hour. Additionally, parallel runs of SARS-CoV-2 detection within the COV-ID system guarantee speedy bathroom availability for customers.
Manual assortment of stool samples is an uncomfortable and odious process that will restrict the usage of fecal matter for COVID-19 detection. Thus, the pattern assortment process of the COV-ID platform was absolutely automated. This decreased human intervention and elevated affected person compliance.
Furthermore, the bathrooms have to be hygienic and forestall cross-contamination among the many COVID-19 check samples. This prerequisite might be met through the use of ultraviolet sterilizers for rigorous sanitization of bathroom surfaces and analytical units within the COV-ID platform.
Smart bathrooms being an Internet of Things (IoT) technology-based system should have the ability to securely hook up with centralized tracing networks to allow energetic person participation and help dedication of COVID-19 epidemiology that will help in formulating COVID-19 pointers and forestall outbreaks sooner or later. This was met through the use of centralized tracing and transferring data by way of Bluetooth to Google and Apple smartphone units within the COVI-ID platform.
Another vital prerequisite for COV-ID success was the upkeep of person privateness. The sensible bathroom platform would de-identify particular person person data and solely add them to the centralized tracing community if the person elected to supply their cellular phone numbers.
In addition to COVID-19 analysis, the COV-ID platform might present supplemental data on the oxygen saturation ranges and physique temperature, that are vital parameters to evaluate COVID-19 severity. The COV-ID platform additionally enabled the evaluation of stool morphology, which might detect diarrhea, a possible COVID-19 symptom.
To conclude, in response to the examine findings, the COV-ID sensible bathroom platform gives a non-invasive, speedy, and handy method for passive and longitudinal monitoring of COVID-19. This platform permits early COVID-19 detection in asymptomatic contaminated people and thereby facilitates the prevention of potential outbreaks. However, the platform’s success largely will depend on person consent and acceptance.